Jackie Trad, who is also the state's treasurer, will step down from her role heading up the government's $5.4 billion Cross River Rail project while the Crime and Corruption Commission investigates.

"I want this resolved as quickly as possible and so I have decided to refer this to the CCC to consider whether it's a matter that requires investigation," Ms Trad said in a statement on Monday.

"I made clear my intention to sell the property when the outcome of the CCC consideration is known."

She said Integrity Commissioner Nikola Stepanov has looked into the matter but has advised against releasing her advice while it is investigated by the CCC.

Opposition leader Deb Frecklington called for the public release of the advice and for Premier Annastacia Palaszczuk to sack her deputy.

She said Ms Trad's announcement would serve as a "smokescreen" to dodge questions when she faces budget estimates from Tuesday.

"It is no coincidence this move came less than 24 hours before Jackie Trad was due to be grilled in Parliament," Ms Frecklington said.

"I had already referred Jackie Trad to the CCC four days ago because of this blatant breach of integrity rules."

The Woolloongabba house was not declared on the Queensland Parliament's register of members' interests within the required time frame.

The Cross River Rail is a underground rail line currently being built in Brisbane.

Ms Frecklington said last week there is a potential increase in value or rezoning of properties close to the rail line.

Australian Associated Press